MECHANISM OF
ACTION

Multiple mechanisms of action including support
across the gut-brain axis1-8,*

MECHANISM
OF ACTION

Multiple mechanisms of action
including support across the gut-
brain axis1-8,*

 

 

 

 

 

 

 

HOW IBEROGAST WORKS

IberogastTM supports gut function,6 the gut microbiome,7,8,† and the gut-brain interaction.4,5,*

HELPS REDUCE STOMACH ACID*

IberogastTM helps increase mucus production in the stomach, while reducing acid secretion.1,*

HELPS REGULATE STOMACH MUSCLES*

IberogastTM has been shown to support motility. It acts by targeting smooth muscle cells within the stomach, relaxing the fundus and increasing contractility of the antrum.2,3,*

HELPS CALM GUT NERVES*

IberogastTM soothes gut nerves to support the gut-brain interaction.4,5,*

HELPS SUPPORT GUT LINING*

IberogastTM supports the normal function of tight junctions.6,*

HELPS SUPPORT GUT
MICROBIOME†,*

IberogastTM causes no drastic shifts in duodenal microbiota and helps promote beneficial bacteria and fermentation products (short-chain fatty acids) in the gut.7,8,*

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Refers to good bacteria and metabolites.

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Click to expand.

    References: 1. Khayyal MT, El-Ghazaly MA, Kenawy SA, et al. Arzneimittelforschung. 2001;51(7):545-553. doi:10.1055/s-0031-1300078 2. Schemann M, Landmann M, Kelber O, Ammar RM, Krueger D, Michel K. Neurogastroenterol Motil. 2021;33(2):e13984. doi:10.1111/nmo.13984 3. Fitzgerald PCE, Bitarafan V, Omari T, et al. Abstract presented at: DDW 2023; May 8, 2023; Chicago, IL. 4. Mueller MH, Gong Q, Kelber O, et al. Neurogastroenterol Motil. 2009;21(4):467–476. doi:10.1111/j.1365-2982.2008.01232.x 5. Mohammadi E, Yuan T, Ligon CO, Rabini S, Ammar RM, Greenwood-Van Meerveld B. Gastroenterology. 2022;162(7 suppl):S-92. doi:10.1016/S0016-5085(22)60233-6 6. Elbadawi M, Ammar RM, Aziz-Kalbhenn H, et al. Phytomedicine. 2021;88:153589. doi:10.1016/j.phymed.2021.153589 7. Ammar RM, Pferschy-Wenzig E-M, Van den Abbeele P, et al. Abstract presented at: DDW 2022; May 21-24, 2022; San Diego, CA. 8. Schooth L, Fairlie T, Lim Y, et al. United European Gastroenterol J. 2022;10(suppl 8):481. 9. Drossman DA, Hasler WL. Gastroenterology. 2016;150(6):1257-1261. doi:10.1053/j.gastro.2016.03.035 10. Schneider M, Efferth T, Abdel-Aziz H. Front Pharmacol. 2016;7:393. doi:10.3389/fphar.2016.00393 11. Tziatzios G, Gkolfakis P, Papanikolaou IS, et al. Microorganisms. 2020;8(5):691. doi:10.3390/microorganisms8050691 12. Zhou L, Zeng Y, Zhang H, Ma Y. Front Physiol. 2022;13:910568. doi:10.3389/fphys.2022.910568

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